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In vitro enzymatic degradation of PCL/HA scaffolds for bone tissue engineering.

Enabling technologies

Research into novel biomaterials and tissue scaffolds provides the basis to innovate cell culture techniques and the ability to approximate more natural tissue environments, which can enhance the growth of specific cell types and enable regeneration.

Our expertise



  • Paulo Jorge da Silva Bartolo

    View Paulo’s research profile.

    Paulo works on the design and fabrication of novel printing systems, and the use of additive manufacturing for tissue engineering with two main approaches: scaffold-based and cell laden.

  • Jonny Blaker

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    Jonny works on hierarchical and stimulatory (bio-active) fibre scaffolds for regenerative medicine, nanofibre spinning technologies and inks for 3D bio printing. His research includes peripheral nerve regeneration, skin regeneration and coronary arteries.

  • Christopher Blanford

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    Christopher’s group studies the synthesis of functional materials suitable for tissue engineering applications. The group also uses quartz crystal microbalance analyses and electrochemistry to probe and control protein adsorption.

  • Cyrill Bussy

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    Cyrill’s work concentrates on the interaction of nanomaterials with adult stem cells in vitro and in vivo niche.

  • Matthew Daniels

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    Matthew makes and applies genetically encoded probes to monitor cardiomyocyte function in living cells in the dish, or the whole animal.

  • Philip Day

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    Philip works on quantitative integrative analyses of bioanalyses, pathway function/ mechanism analysis, microbiome and chronic inflammatory diseases, miniaturisation for single cell studies, role of biological heterogeneity, systems biology and synthetic biology applications

  • Sarah Cartmell

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    Sarah’s work focuses on electrical stimulation for orthopaedic and peripheral nerve tissue regeneration, and scaffold manufacture and characterisation including micro CT imaging development.

  • Brian Derby

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    Brian works on bioprinting (3D Printing) to promote vascularisation and innervation; building tissue models and organ-on-a-chip; biomechanics and mechanical properties of cells and ECM and tissues.

  • Rania Deranieh

    Rania develops cancer and human stem cell-derived 3D culture models (spheroids and organoids) to study the interaction of human cells with nanomaterials and to develop novel theranostics.

  • Marco Domingos

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    Marco works on the development and application of advanced 3D Bioprinting platforms for Regenerative Medicine and Tissue Engineering therapies.

  • Lee Fielding

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    Research in the Fielding Lab focusses on the preparation of bespoke polymeric materials for a range of applications including regenerative medicine.

  • James Fildes

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    James develops technologies to improve and prolong the preservation of donor organs and tissues using ex-vivo perfusion, which can be used across transplantation, trauma, and wound healing.

  • Sergio Oliveira Formoso

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    Sergio’s work focuses on biomaterial-based platforms to aid in regeneration of peripheral nerves as the potential key points in regenerative medicine.

  • Peter Gardner

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    Peter works in infrared and Raman imaging of biological tissue and cells and is interested in 3D printing of tissue.

  • Julie Gough

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    Professor Gough’s research encompasses controlling cell responses at the cell-biomaterial interface by engineering defined surfaces and developing scaffolds for tissue repair such as novel hydrogels and various porous and fibrous materials.

  • Aline Miller

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    Aline designs, synthesises and tests peptide based biomaterials with controllable mechanical and functional properties for use within 3D tissue engineering, drug delivery and incorporation within medical devices.

  • Stephen Richardson

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    Dr Richardson works on adult human multipotent stem cells and their application in regenerative therapies for musculoskeletal tissues, including intervertebral disc, articular cartilage and bone.

  • Alberto Saiani

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    Alberto designs and develops novel functional and biocompatible peptide based soft and injectable hydrogels for biomedical applications, e.g. for drug/cell topical delivery, 3D cell culture, disease modelling and 3D bioprinting.

  • Joe Swift

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    Joe focuses on understanding how chemical and mechanical signals from the cellular microenvironment control cell behaviour.

  • Annalisa Tirella

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    Annalisa’s work covers biomaterials controlled in physical properties to promote cell adhesion, migration and differentiation. She also works with alginates-based hydrogels and high throughput 3D in vitro models.

  • Olga Tsigkou

    View Olga’s research profile.

    Olga focuses on the combination of scaffolds with hydrogels, stem cells and 3D cell culture for tissue regeneration, predominantly bone tissue. Her group developed robust protocols for disease modelling.

  • Aravind Vijayaraghavan

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    Aravind’s work focuses on tissue scaffolds and biosensors based on graphene and related nanomaterials, and understanding the fundamentals of interaction between bio-molecules and cells with nanomaterials.

  • Thomas Waigh

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    Thomas is interested in bacterial biofilms and peptides for wound healing.

  • Simon Webb

    Simon focuses on developing new wound care materials through chemical modification and creating self-assembled hydrogels for applications in cell culture.

  • Lu Shin Wong

    View Lu Shin’s research profile.

    Lu Shin develops novel materials for the study and manipulation of cells for applications in regenerative medicine, employing chemical synthetic and nanolithography tools for use in vitro cell studies.