Skin and wound healing
Manchester has a strong history of wound healing research with robust clinical links. Our research extends from acute to chronic wounds, to scarring, fibrosis and healing mechanisms.
Enrique’s work focuses on mechanisms that trigger and sustain a regenerative response, especially during appendage and heart regeneration.
Ardeshir works on tissue repair, fibrosis and regeneration, identifying gene and protein diagnostic biomarkers (skin scarring and chronic wounds), novel targets and therapeutic modalities for abnormal wound healing and skin fibrosis.
Anthony is developing a protein-based biological drug with anti-inflammatory and tissue-protective properties. He is also studying the role of glycosaminoglycan-protein interactions in inflammation, tissue organisation and stem cell biology.
James develops technologies to improve and prolong the preservation of donor organs and tissues using ex-vivo perfusion, which can be used across transplantation, trauma, and wound healing.
View Sarah’s research profile.
Sarah’s research focuses on understanding the fundamental cellular and molecular mechanisms involved in tissue repair, the way these processes are linked to excessive healing and identifying ways of regulating these processes therapeutically.
Svitlana uses modified antisense oligonucleotides for efficient delivery, tracking, and downregulation of miRNAs in cultured primary human skin cells and in mouse wound healing model in vivo. She is establishing miRNA crosslinking and immunoprecipitation (miR-CLIP) to identify new RNAs regulating growth and differentiation of cells essential for the improvement of cutaneous regeneration.
View Kim's research profile.
Kim’s work focuses on the role of inflammation during wound healing and how this can be manipulated therapeutically, particularly in the context of impaired healing due to ageing and diabetes.
Qing-Jun’s research focuses on 24 hour circadian rhythms and their roles in temporally regulating tissue homeostasis, repair and regeneration.
Michael works on the development of new biochemical, biomechanical and biophysical approaches to characterising tissue degeneration and inducing tissue repair
Andrew specialises in surface spectroscopy, applicable to polymer/metal/metal oxide substrates and wound healing. He works on understanding peptide/protein interaction with non-biological materials on the molecular/nanoscale.
View Thomas’ research profile.
Thomas is interested in bacterial biofilms and peptides for wound healing.
View Jason’s research profile.
Jason works on translating soft tissue, vascular, and composite tissue bioscience towards clinical benefit of injured, wounded and traumatised patients. This includes understanding tissue scarring, complex wounds and the biomechanics of rehabilitation.
Julian specialises in oro-facial reconstruction and soft and hard tissue regeneration.